Increased interleukin-17 production in patients with systemic sclerosis

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Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease?

Title Clinical association of serum interleukin 17 levels in systemic sclerosis: Is systemic sclerosis a Th17 disease? Author(s) Murata, Maki; Fujimoto, Manabu; Komura, Kazuhiro; Matsushita, Takashi; Hamaguchi, Yasuhito; Hasegawa, Minoru; Sato, Shinichi; Takehara, Kazuhiko Citation Journal of Dermatological Science, 50(3), pp.240-242; 2008 Issue Date 2008-03-07 URL http://hdl.handle.net/10069/1...

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Serum Interleukin-17 Evaluation in Patients With Eosinophilic Gastrointestinal Disease

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Increased endothelin-1 production in fibroblasts derived from patients with systemic sclerosis.

OBJECTIVES To determine whether fibroblasts from patients with systemic sclerosis (SSc) produce excessive amounts of endothelin-1 (ET-1), which is recognised as having vasoconstrictive properties and as having a potent mitogenic effect on fibroblasts. METHODS Dermal fibroblasts were removed from 11 patients with SSc and from five normal controls (NC). The assay of ET-1 protein was measured by...

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Interleukin 17 production among patients with American cutaneous leishmaniasis.

Interleukin 17 (IL-17) plays a critical role in inflammation and autoimmunity. Very little is known about IL-17 in protozoa infection. Here, we show that lymphocytes obtained from patients with mucosal leishmaniasis and cutaneous leishmaniasis produce higher levels of IL-17 than do lymphocytes obtained from uninfected control subjects (P<.01). There was a tendency for tissue obtained from patie...

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Pulmonary hypertension in systemic sclerosis: an analysis of 17 patients.

A retrospective chart review was carried out on 344 patients with systemic sclerosis (SSc) followed prospectively for the occurrence of pulmonary hypertension (PHT). Seventeen patients (4.9%) were found to have PHT. Eight patients had isolated PHT, while in nine PHT was associated with restrictive lung disease (RLD). The subset with RLD developed PHT earlier, but had longer survival than patien...

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ژورنال

عنوان ژورنال: Arthritis & Rheumatism

سال: 2000

ISSN: 0004-3591,1529-0131

DOI: 10.1002/1529-0131(200011)43:11<2455::aid-anr12>3.0.co;2-k